Literature review tool that maps related papers by their citations, with search, monitoring alerts, sharing and Zotero sync.

Synthesa
AI-assisted evidence synthesis service for systematic reviews, abstract screening and meta-analysis.
What is Synthesa?
Synthesa provides evidence synthesis as a managed service that combines AI-powered workflows with expert review. Clients such as contract research organizations, medical communications agencies, and pharma, medical device, biotech and medtech groups define a research question, PICO criteria and outputs, and Synthesa handles the repetitive stages. Those include search strategy generation, high-volume title and abstract screening, data extraction, assessment of bias risk and frequentist or Bayesian meta-analysis, network meta-analysis and meta-regression. Experts check screening decisions, extracted variables and statistical assumptions before results are delivered as screened records, evidence maps, narrative synthesis or decision-focused briefs. The site reports an average delivery of 7 to 14 days and offers a free abstract screening pilot run on your own search strategy. Prices are not published; projects are scoped on a call.
Use cases
- Screen thousands of abstracts for a review
- Run a systematic literature review
- Perform Bayesian or frequentist meta-analysis
- Run a network meta-analysis
- Extract data from clinical studies
- Assess risk of bias across studies
- Generate a search strategy
Who it's for
Why use Synthesa
- Large literature sets can be screened without growing an internal team.
- The site gives an average delivery time of 7 to 14 days.
- Screening decisions come with transparent inclusion and exclusion reasons.
- A free pilot lets you compare the output with your own screening team.
Synthesa features
- Search strategy generation
- High-volume abstract screening
- Data extraction from studies
- Risk of bias assessment
- Frequentist and Bayesian meta-analysis
- Network meta-analysis and meta-regression
- Evidence mapping and narrative synthesis
- Expert validation of screening, extraction and statistics
- Free abstract screening pilot
How to get started with Synthesa
- Share your research question, PICO criteria, search strategy and required outputs.
- Synthesa organizes the inputs, such as search exports and prior screening decisions, into a project workflow.
- AI-powered workflows handle screening and structured extraction at scale.
- Experts review the outputs, then deliver the synthesis, meta-analysis or evidence brief.
Synthesa limitations
- Delivered as a managed service, not a self-serve tool
- Prices are not published; projects are scoped on a call
- The free pilot covers abstract screening only
Synthesa pricing
Synthesa is sold on custom quotes, so its prices aren't published.
Prices can change and may vary by country or exclude tax. Check the official pricing page.
Synthesa alternatives
The main Synthesa alternatives listed on Debuly are Rayyan, Elicit, AnswerThis, Consensus, CreativAI and QuantLink. The table compares pricing and platforms; order is A–Z.
| Tool | Pricing | Starting price | Platforms |
|---|---|---|---|
| Synthesa | Contact sales | — | — |
| AnswerThis | Freemium | $35/mo | Web |
| Consensus | Freemium | $12/mo | Web, API, MCP |
| CreativAI | Freemium | $180/yr | Web, API |
| Elicit | Freemium | $49/mo | Web, API |
| QuantLink | Free trial | $100/mo | Web, API |
| Rayyan | Freemium | $8.33/mo | Web, iOS, Android |

AnswerThis
AnswerThis is an AI research assistant that searches 250M+ papers, writes cited literature reviews and runs systematic reviews.
FreemiumVisit AnswerThis (official site)
Consensus
AI search engine for research that answers questions from peer-reviewed papers, with every claim linked back to its source.
FreemiumVisit Consensus (official site)
CreativAI
Video intelligence platform that indexes footage and images so you can search, chat with and extract data from them.
FreemiumVisit CreativAI (official site)
Elicit
AI research assistant that searches 138 million papers, extracts data into tables and runs systematic reviews and cited reports.
FreemiumVisit Elicit (official site)
QuantLink
AI equity research workstation with screeners, portfolios, dashboards and deep research reports for individual investors and fund teams.
Free trialVisit QuantLink (official site)
Rayyan
Web and mobile platform for systematic and literature reviews, with deduplication, screening, relevance ranking and team collaboration.
FreemiumVisit Rayyan (official site)
Synthesa FAQ
How much does Synthesa cost?
No prices are published. Work is scoped per project, and the site invites visitors to book a call or start with a free pilot.
Is there a free option for Synthesa?
Yes. It offers a free abstract screening pilot using your search strategy and PICO criteria, which can run alongside your human team or against a finished project.
Who is Synthesa for?
CROs and medcomms agencies, pharma and medical affairs teams, medical device companies, and biotech or medtech startups.
What analyses does Synthesa support?
Frequentist and Bayesian meta-analysis, network meta-analysis and meta-regression, plus risk of bias assessment and data extraction.
What are alternatives to Synthesa?
Covidence, Rayyan, DistillerSR, Elicit and Nested Knowledge cover screening and review workflows, usually as software your team operates itself.
Sources & verification
Facts on this page come from the official sources below, each with the date we read it. Written by Debuly; the vendor did not review this page.
| Source | Type | Accessed |
|---|---|---|
| synthesa.ai/ | official | |
| synthesa.ai/pricing | pricing | |
| synthesa.ai/how-it-works/ | official |
Image credits
- Logo: from synthesa.ai · fetched · Vendor trademark, used only to identify the product; removed on request
- Cover: none collected yet, so a generated tile is shown.
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